ethyl 2-chloro-4-phenylpyrimidine-5-carboxylate - Names and Identifiers
ethyl 2-chloro-4-phenylpyrimidine-5-carboxylate - Physico-chemical Properties
Molecular Formula | C13H11ClN2O2
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Molar Mass | 262.69 |
Storage Condition | 2-8℃ |
ethyl 2-chloro-4-phenylpyrimidine-5-carboxylate - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
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HS Code | 29339900 |
ethyl 2-chloro-4-phenylpyrimidine-5-carboxylate - Introduction
Ethyl 4-phenyl-2-chloropyrimidine-5-carboxylate is an organic compound with the chemical formula C15H11ClN2O2. The following is a detailed description of its properties, uses, preparation methods and safety information:
Nature:
Ethyl 4-phenyl-2-chloropyrimidine-5-carboxylate is a colorless to slightly yellow solid. It is almost insoluble in water at normal temperature, but soluble in organic solvents such as ethanol, dimethylformamide and chloroform. It is a medium-strength acid that can form salts and esters.
Use:
4-phenyl -2-chloropyrimidine -5-carboxylic acid ethyl ester is commonly used as an intermediate in organic synthesis. It can be used to synthesize a variety of compounds, such as organic dyes, drugs and pesticides. In addition, it can also be used as a raw material for fungicides and herbicides.
Preparation Method:
A common preparation method is to react phenylethyl alcohol with 2-chloropyrimidine in the presence of a certain catalyst to obtain 4-phenyl-2-chloropyrimidine. 4-Phenyl-2-chloropyrimidine is then reacted with chloroacetic acid in the presence of a basic catalyst to give ethyl 4-phenyl-2-chloropyrimidine-5-carboxylate.
Safety Information:
Ethyl 4-phenyl-2-chloropyrimidine-5-carboxylate is generally relatively safe under normal use and storage conditions. However, it is an organic compound and should comply with relevant safety procedures and maintain good ventilation conditions. Avoid contact with skin, eyes and respiratory tract. If inhaled or in contact with skin, rinse immediately with water and seek medical help.
Last Update:2024-04-09 20:52:54